Welcome to the Web Site of the Inner-City Asthma Study (ICAS)

ICAS Staff login here.

ICAS is a 7-site cooperative study sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH). ICAS was designed to evaluate the effectiveness of two types of interventions to reduce asthma morbidity and severity among 937 inner-city children, ages 5-11, with moderate to severe asthma. Each participant was enrolled for two years, the intervention year and a follow-up year. An Environmental Intervention and a Physician Feedback Intervention were studied using a 2x2 factorial design.

The Physician Feedback intervention entailed a novel communication and education system that provided physicians with up-to-date information on the child's symptoms, medication use, and health care utilization. The Environmental Intervention focused on the home environments of the children, involving education and remediation of environmental exposures including cockroaches, dust mites, environmental tobacco smoke (ETS), mold, furry pets, and rodents.

ICAS Principal Investigators:
  • Ellen F. Crain, MD, PhD
  • Albert Einstein College of Medicine, Bronx
  • Richard Evans III, MD, MPH
  • Northwestern Univ. Medical School, Chicago
  • Rebecca S. Gruchalla, MD, PhD
  • U.T. Southwestern Medical Center, Dallas
  • Meyer Kattan, MD, CM
  • Mt. Sinai School of Medicine, New York
  • Wayne Morgan, MD, CM
  • Univ. of Arizona College of Medicine, Tucson
  • George T. O'Connor, MD, MS
  • Boston Univ. School of Medicine, Boston
  • James W. Stout, MD, MPH
  • Univ. of Washington School of Medicine, Seattle

    ICAS Data Coordinating Center Principal Investigator:
  • Herman Mitchell, PhD
  • Rho Federal Systems Division, Chapel Hill, NC

    ICAS Project Officers:
  • Ernestine Smartt, RN
  • National Institute of Allergy and Infectious Diseases
  • J. Patrick Mastin, PhD
  • National Institute of Environmental Health Sciences

    Questionnaires that were used in ICAS are available below. To view and/or print a form, click on its link below.

    For information regarding the ICAS project please contact:

    Please contact us for any technical question.